3-Amino-5-bromo-2-methylpyridine

Name: 3-Amino-5-bromo-2-methylpyridine
Brand: ChemScene
Availability: InStock
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CAS No. 914358-73-9
Cat. No. CS-W003575
Purity≥95%
MDL No.MFCD09031418

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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3-Amino-5-bromo-2-methylpyridine|CS-W003575

Structure of 914358-73-9

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Description

3-Amino-5-bromo-2-methylpyridine features a strategically positioned amino group and bromine atom on a pyridine scaffold, enabling selective functionalization in cross-coupling reactions. The methyl substituent enhances electronic modulation and solubility, supporting efficient integration into pharmaceutical intermediates and advanced materials under standard conditions.

Application

3-Amino-5-bromo-2-methylpyridine serves as a versatile building block in medicinal chemistry and heterocyclic synthesis, enabling direct functionalization at multiple sites. The amino group facilitates nucleophilic substitution and coupling reactions, while the bromo substituent supports palladium-catalyzed cross-coupling transformations. Its methyl group enhances metabolic stability and modulates electronic properties. This compound exhibits excellent bench stability and is readily purified by recrystallization or column chromatography, making it ideal for scalable synthesis of pyridine-based pharmaceutical intermediates.

General Information

CAS No. 914358-73-9
Cat. No. CS-W003575
Purity ≥95%
MDL No. MFCD09031418
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₇BrN₂
Molecular Weight 187.04
Synonym(s) 3ABMP
SMILES BrC1=CN=C(C)C(N)=C1

Computational Chemistry Data

TPSA 38.91
LogP 1.73472
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Bioactive Molecules Dye and Bio-assay Reagents

Building Blocks Functional Group Amine

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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3-Amino-5-bromo-2-methylpyridine

CAS No. 914358-73-9

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