(S)-1-(5-Bromopyridin-2-yl)ethan-1-amine

Name: (S)-1-(5-Bromopyridin-2-yl)ethan-1-amine
Brand: ChemScene
Availability: InStock
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CAS No. 915720-70-6
Cat. No. CS-0143802
Purity≥97%
MDL No.MFCD09256735

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(S)-1-(5-Bromopyridin-2-yl)ethan-1-amine|CS-0143802

Structure of 915720-70-6

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Description

(S)-1-(5-Bromopyridin-2-yl)ethan-1-amine is a chiral building block featuring a brominated pyridine ring coupled to a stereodefined ethylamine side chain. This configuration enables selective coupling in asymmetric synthesis, particularly for pharmaceutical intermediates requiring defined stereochemistry. The molecule exhibits enhanced reactivity at the pyridine nitrogen and stable handling under standard bench conditions.

Application

(S)-1-(5-Bromopyridin-yl)ethan-1-amine serves as a versatile building block in medicinal chemistry, enabling the synthesis of pyridine-containing bioactive molecules via palladium-catalyzed cross-coupling reactions. The chiral α-amino group provides stereochemical control, while the bromopyridine moiety offers high reactivity in Suzuki, Stille, and Negishi couplings. Its bench-stable crystalline form facilitates handling and purification, making it ideal for modular scaffold construction in drug discovery programs.

General Information

CAS No. 915720-70-6
Cat. No. CS-0143802
Purity ≥97%
MDL No. MFCD09256735
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₉BrN₂
Molecular Weight 201.06
Synonym(s) (S)-1-(5-Bromo-pyridin-2-yl)-ethylamine
SMILES N[C@H](C1=NC=C(Br)C=C1)C

Computational Chemistry Data

TPSA 38.91
LogP 1.8638
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(S)-1-(5-Bromopyridin-2-yl)ethan-1-amine

CAS No. 915720-70-6

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