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Structure of 91678-81-8
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3,5-Dimethylpyrazin-2-amine features a pyrazine core substituted with methyl groups at positions 3 and 5 and an amino group at position 2. This electron-rich heterocycle integrates readily into transition metal-catalyzed coupling reactions, offering enhanced solubility and stability under standard conditions. The para-substitution pattern enables efficient coordination in catalytic systems, particularly in palladium-catalyzed cross-couplings.
3,5-Dimethylpyrazin-2-amine serves as a versatile building block in medicinal chemistry, enabling the construction of heterocyclic scaffolds through standard coupling and functionalization reactions. Its pyrazine core exhibits favorable bench stability and tolerates a range of reaction conditions, facilitating downstream derivatization. The strategically positioned amine group supports direct incorporation into peptide-like architectures or conjugation via amide bond formation.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: