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Structure of 917505-12-5
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(S)-1-(Pyrrolidin-3-yl)piperidine dihydrochloride features a chiral piperidine core fused to a pyrrolidine ring, delivering enhanced conformational rigidity and improved binding affinity. This bench-stable salt form enhances solubility and handling in synthetic workflows, enabling efficient incorporation into bioactive scaffolds for medicinal chemistry applications.
(S)-1-(Pyrrolidin-3-yl)piperidine dihydrochloride serves as a versatile chiral building block in medicinal chemistry, enabling the construction of complex nitrogen-containing scaffolds. Its rigidified piperidine core with stereogenic center facilitates controlled conformational presentation in bioactive molecules. The dihydrochloride salt enhances solubility and stability for handling, while the amine functionalities support straightforward derivatization via alkylation, acylation, or coupling reactions. This compound functions effectively in the synthesis of targeted API candidates requiring defined stereochemistry and improved pharmacokinetic profiles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: