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CS-W001157 4
Total: USD 88.00

(R)-1-Methyl-4-(pyrrolidin-3-yl)piperazine trihydrochloride

  • CAS No. 917505-14-7

  • Cat. No. CS-0698176
  • Purity≥98%
  • MDL No.None
  • HazMat Fee +

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    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(R)-1-Methyl-4-(pyrrolidin-3-yl)piperazine trihydrochloride|CS-0698176

Structure of 917505-14-7

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Description

(R)-1-Methyl-4-(pyrrolidin-3-yl)piperazine trihydrochloride is a chiral piperazine derivative featuring a tertiary amine center and a pyrrolidinyl substituent. This bench-stable, moisture-tolerant salt integrates readily into medicinal chemistry libraries, offering enhanced solubility and defined stereochemistry for targeted receptor engagement in CNS-directed drug discovery.

Application

(R)-1-Methyl-4-(pyrrolidin-3-yl)piperazine trihydrochloride serves as a versatile, bench-stable building block for medicinal chemistry campaigns. Its tertiary amine core enables straightforward salt formation and enhances solubility in aqueous media. The molecule functions effectively in coupling reactions and supports the construction of complex heterocyclic scaffolds common in CNS-targeted therapeutics. Functional group tolerance and ease of purification make it well-suited for high-throughput synthesis and process-scale applications.

General Information

  • CAS No. 917505-14-7
  • Cat. No. CS-0698176
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₂₂Cl₃N₃
  • Molecular Weight 278.65
  • Synonym(s) None
  • SMILES Cl.Cl.Cl.CN1CCN(CC1)[C@@H]1CCNC1

Computational Chemistry Data

  • TPSA   18.51
  • LogP   0.8611
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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