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CS-W001157 4
Total: USD 88.00

Bicyclohexyl

  • CAS No. 92-51-3

  • Cat. No. CS-0081506
  • Purity≥98%
  • MDL No.MFCD00003815

*For research and further manufacturing use only, not for direct human use.

Bicyclohexyl|CS-0081506

Structure of 92-51-3

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General Information

  • CAS No. 92-51-3
  • Cat. No. CS-0081506
  • Purity ≥98%
  • MDL No. MFCD00003815
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₂
  • Molecular Weight 166.30
  • Synonym(s) Dicyclohexyl
  • SMILES C1(CCCCC1)C2CCCCC2

Description

Methylamino-PEG4-acid HCl salt is a PEG linker containing a carboxylic acid with a methylamine group. The hydrophilic PEG spacer increases solubility in aqueous media. The methylamine group is reactive with carboxylic acids, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Application

Bicyclohexyl serves as a stable, bench-friendly hydrocarbon scaffold enabling controlled steric evaluation in catalytic and organometallic studies. Its rigid, symmetric structure facilitates precise conformational analysis and functions as a reliable ligand platform in transition metal complexes. The molecule exhibits excellent thermal stability and solubility in common organic solvents, simplifying purification and handling in synthetic workflows.

Synthesis

  • Route1

    References

    • Xu, Xiaoliang; Cheng, Dongping; Pei, Wen Journal of Organic Chemistry, 2006 , vol. 71, # 17 p. 6637 - 6639
  • Route2

    References

    • Field, Leslie D.; Sternhell, Sever; Wilton, Howard V. Tetrahedron, 1997 , vol. 53, # 11 p. 4051 - 4062
  • Route3
    • null|null
      931-50-0
    • ~95%
    • In-stock
      Bicyclohexyl|CS-0081506
      92-51-3

    References

    • Nishiyama, Tomihiro; Seshita, Takeshi; Shodai, Hiroshi; Aoki, Kazushige; Kameyama, Hideaki; Komura, Kenichi Chemistry Letters, 1996 , # 7 p. 549 - 550

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS08,GHS09
Signal Word : Warning
UN#: 3082
Class : 9
Packing Group : Ⅲ
Hazard Statements : H227-H302-H304-H335-H400-H411
Precautionary Statements : P210-P261-P264-P270-P271-P273-P280-P304+P340-P330-P331-P370+P378-P391-P403-P405-P501

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Computational Chemistry Data

  • TPSA   0
  • LogP   4.147
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   1

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