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Structure of 920313-51-5
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5-Cyclopropylpyrazin-2-amine features a cyclopropyl group at the 5-position of a pyrazine core, enhancing lipophilicity and metabolic stability. This electron-deficient heterocycle serves as a key scaffold in kinase inhibitor design, offering improved membrane permeability and target engagement.
5-Cyclopropylpyrazin-2-amine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to pyrazine-based scaffolds. Its cyclopropyl substituent enhances metabolic stability and modulates lipophilicity, while the primary amine facilitates downstream functionalization via coupling reactions. The compound exhibits good bench stability and is compatible with standard synthetic workflows, including amide bond formation and Suzuki-Miyaura coupling, making it valuable for the development of API candidates and targeted library synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: