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Structure of 920313-67-3
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tert-Butyl (5-aminopyrazin-2-yl)carbamate features a pyrazine core with orthogonal functional handles: a protected amine at the 5-position and a carbamate group enabling facile deprotection. This bench-stable derivative serves as a key intermediate in the synthesis of bioactive heterocycles, particularly in medicinal chemistry campaigns targeting kinase inhibitors and antitumor agents.
tert-Butyl (5-aminopyrazin-2-yl)carbamate serves as a versatile pyrazine-based building block for medicinal chemistry and process development. The protected amine enables orthogonal functionalization in multistep syntheses, while the pyrazin-2-yl core supports diverse coupling reactions and heterocycle elaboration. Bench-stable and easily purified, it functions effectively in standard amide bond formation, metal-catalyzed cross-couplings, and late-stage derivatization workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: