(S)-tert-Butyl (2-oxopiperidin-3-yl)carbamate

Name: (S)-tert-Butyl (2-oxopiperidin-3-yl)carbamate
Brand: ChemScene
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CAS No. 92235-39-7
Cat. No. CS-B1207
Purity≥97%
MDL No.MFCD08166304

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(S)-tert-Butyl (2-oxopiperidin-3-yl)carbamate|CS-B1207

Structure of 92235-39-7

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Description

(S)-tert-Butyl (2-oxopiperidin-3-yl)carbamate is a chiral building block featuring a protected piperidinone scaffold with defined stereochemistry at the 3-position. This bench-stable, moisture-tolerant reagent integrates seamlessly into peptide synthesis and medicinal chemistry workflows, enabling efficient access to bioactive nitrogen-containing heterocycles through straightforward deprotection and functionalization.

Application

(S)-tert-Butyl (2-oxopiperidin-3-yl)carbamate serves as a key chiral building block in the synthesis of piperidine-containing scaffolds, enabling efficient access to biologically relevant heterocycles. Its stable tert-butyl carbamate group offers excellent protection for primary amines, while the 2-oxo functionality facilitates downstream transformations such as reductive amination and ring expansion. The compound exhibits high bench stability, ease of purification, and compatibility with standard coupling and functionalization protocols, making it well-suited for medicinal chemistry and process development workflows.

General Information

CAS No. 92235-39-7
Cat. No. CS-B1207
Purity ≥97%
MDL No. MFCD08166304
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₈N₂O₃
Molecular Weight 214.26
Synonym(s) (S)-3-(Boc-amino)-2-piperidone
SMILES O=C(OC(C)(C)C)N[C@@H]1C(NCCC1)=O

Computational Chemistry Data

TPSA 67.43
LogP 0.7897
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(S)-tert-Butyl (2-oxopiperidin-3-yl)carbamate

CAS No. 92235-39-7

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