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CS-W001157 4
Total: USD 88.00

7-Bromo-1,3-dichloroisoquinoline

  • CAS No. 924271-40-9

  • Cat. No. CS-0046923
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

7-Bromo-1,3-dichloroisoquinoline|CS-0046923

Structure of 924271-40-9

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General Information

  • CAS No. 924271-40-9
  • Cat. No. CS-0046923
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₄BrCl₂N
  • Molecular Weight 276.94
  • Synonym(s) 7-Bromo-1,3-dichloro-2-azanaphthalene
  • SMILES ClC1=NC(Cl)=CC2=CC=C(C=C12)Br

Description

7-Bromo-1,3-dichloroisoquinoline is a halogenated isoquinoline scaffold featuring strategic substitution at the 7-position (bromine) and 1,3-positions (chlorines), enabling selective coupling reactions in synthetic medicinal chemistry. This electron-deficient framework facilitates palladium-catalyzed cross-couplings and serves as a key building block for bioactive heterocycles.

Application

7-Bromo-1,3-dichloroisoquinoline serves as a versatile building block for the synthesis of substituted isoquinoline scaffolds. The bromo group enables palladium-catalyzed cross-coupling reactions, while the dichloro substitution pattern facilitates selective functionalization under controlled conditions. Its bench-stable nature and compatibility with standard coupling protocols make it well-suited for medicinal chemistry campaigns and heterocyclic library development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   4.3041
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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