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Structure of 925441-35-6
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4-Fluoro-2,6-dimethylbenzaldehyde features a fluorinated aromatic core with strategically positioned methyl groups, delivering enhanced electron deficiency at the aldehyde site. This combination enables efficient coupling in cross-coupling reactions and facilitates selective functionalization in synthetic sequences. The molecule exhibits robust stability under standard conditions, simplifying handling and integration into multi-step syntheses.
4-Fluoro-2,6-dimethylbenzaldehyde serves as a versatile building block in medicinal chemistry and agrochemical synthesis, offering enhanced metabolic stability through fluorine substitution. Its ortho-methyl groups provide steric shielding, improving bench stability and facilitating selective functionalization. The aldehyde group enables reliable imine formation, reductive amination, and Ugi-type condensations, while the electron-withdrawing fluorine modulates electrophilicity for controlled reactivity in cross-coupling and nucleophilic addition processes.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: