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Structure of 925672-88-4
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5-Bromo-2-cyanobenzeneacetonitrile features a dual nitrile group flanking a brominated aromatic ring, enabling versatile coupling reactions. The electron-deficient aryl halide facilitates palladium-catalyzed cross-couplings, while the acetonitrile side chain offers a handle for further functionalization. This compound serves as a key intermediate in synthesizing bioactive heterocycles and advanced materials.
5-Bromo-2-cyanobenzeneacetonitrile serves as a versatile building block in medicinal chemistry and materials science, enabling palladium-catalyzed cross-coupling reactions due to its dual electrophilic sites. The cyano group enhances reactivity in nucleophilic substitutions, while the bromine facilitates C–C bond formation under standard Suzuki or Stille conditions. Bench-stable and amenable to purification via flash chromatography, it functions effectively in the synthesis of substituted heterocycles and functionalized aryl scaffolds relevant to API development.
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GHS No : GHS06
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Signal Word : Danger
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UN#: 3439
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H302+H312-H315-H319-H331-H335
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: