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CS-W001157 4
Total: USD 88.00

3,6-Dichloro-4-fluoropyridazine

  • CAS No. 92920-33-7

  • Cat. No. CS-0051594
  • Purity≥96%
  • MDL No.MFCD21648467

*For research and further manufacturing use only, not for direct human use.

3,6-Dichloro-4-fluoropyridazine|CS-0051594

Structure of 92920-33-7

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General Information

  • CAS No. 92920-33-7
  • Cat. No. CS-0051594
  • Purity ≥96%
  • MDL No. MFCD21648467
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄HCl₂FN₂
  • Molecular Weight 166.97
  • Synonym(s) Pyridazine,3,6-dichloro-4-fluoro
  • SMILES FC1=CC(Cl)=NN=C1Cl

Description

3,6-Dichloro-4-fluoropyridazine is a halogenated pyridazine derivative featuring complementary reactivity at the 3,6-dichloro and 4-fluoro positions. This electron-deficient heterocycle integrates readily into synthetic sequences requiring selective substitution or coupling under mild conditions. The molecule exhibits enhanced stability and compatibility with diverse reaction environments, enabling efficient access to functionalized intermediates in medicinal chemistry and agrochemical research.

Application

3,6-Dichloro-4-fluoropyridazine serves as a versatile building block in medicinal chemistry, enabling late-stage functionalization via palladium-catalyzed cross-coupling reactions. The orthogonal reactivity of its chloro and fluoro substituents facilitates sequential derivatization, while its bench-stable nature supports reliable handling and purification. This compound functions as a key scaffold for constructing bioactive heterocycles in API development.

Safety Information

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GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2810
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H311-H331
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P405-P501

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Computational Chemistry Data

  • TPSA   25.78
  • LogP   1.9225
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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