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Structure of 929288-22-2
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4-Amino-2,6-dichloronicotinic acid features a conjugated pyridine core bearing two chlorine substituents and a primary amine group, enabling direct integration into diverse heterocyclic scaffolds. This electron-deficient framework supports efficient coupling reactions under mild conditions, offering enhanced solubility in polar solvents and stability during synthetic manipulations.
4-Amino-2,6-dichloronicotinic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its orthogonal functional groups—amino and carboxylic acid—facilitate efficient derivatization via amide coupling, amidation, or electrophilic substitution. The dichloro substitution pattern enhances reactivity in cross-coupling processes and supports structural diversification for target-focused libraries. Bench-stable and readily purified by crystallization, it functions reliably in standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: