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CS-W001157 4
Total: USD 88.00

2-(3-Chloro-5-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

  • CAS No. 929626-16-4

  • Cat. No. CS-0174431
  • Purity≥98%
  • MDL No.None
  • HazMat Fee +

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    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-(3-Chloro-5-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane|CS-0174431

Structure of 929626-16-4

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Description

This boronate reagent features a chloro-methoxy-substituted aryl group enabling efficient cross-coupling in Suzuki-Miyaura reactions. The tetramethyl-dioxaborolane scaffold ensures excellent stability, solubility in common organic solvents, and compatibility with air- and moisture-tolerant protocols.

Application

2-(3-Chloro-5-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane serves as a stable, bench-ready boronate building block for Suzuki-Miyaura cross-coupling reactions. The 3-chloro-5-methoxyphenyl moiety enables selective functionalization under standard catalytic conditions, with the tetramethyl-substituted dioxaborolane ring providing enhanced stability and ease of purification. Its compatibility with diverse reaction partners makes it a practical choice for constructing complex aryl architectures in medicinal chemistry and materials synthesis.

General Information

  • CAS No. 929626-16-4
  • Cat. No. CS-0174431
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₈BClO₃
  • Molecular Weight 268.54
  • Synonym(s) 3-CHLORO-5-METHOXYPHENYLBORONIC ACID, PINACOL ESTER
  • SMILES CC1(C(C)(OB(O1)C2=CC(Cl)=CC(OC)=C2)C)C

Computational Chemistry Data

  • TPSA   27.69
  • LogP   2.6478
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P405-P501

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