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Potassium benzofuran-2-yltrifluoroborate

  • CAS No. 929626-27-7

  • Cat. No. CS-0199492
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Potassium benzofuran-2-yltrifluoroborate|CS-0199492

Structure of 929626-27-7

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General Information

  • CAS No. 929626-27-7
  • Cat. No. CS-0199492
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅BF₃KO
  • Molecular Weight 224.03
  • Synonym(s) Potassium 2-benzofuranyltrifluoroborate
  • SMILES C1=CC=C2C(=C1)C=C([B-](F)(F)F)O2.[K+]

Description

Potassium benzofuran-2-yltrifluoroborate serves as a stable, bench-ready boronate reagent for palladium-catalyzed cross-coupling reactions. This trifluoroborate derivative features a fused benzofuran core with enhanced solubility and resistance to hydrolysis, enabling efficient incorporation into complex molecular architectures under mild reaction conditions.

Application

Potassium benzofuran-2-yltrifluoroborate serves as a stable, bench-ready boron building block for Suzuki-Miyaura cross-coupling reactions. Its trifluoroborate group enables efficient C–C bond formation under mild conditions, offering excellent functional group tolerance and compatibility with diverse aryl halides. The compound facilitates the construction of biaryl scaffolds prevalent in pharmaceutical and agrochemical research, with predictable reactivity and straightforward purification.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   13.14
  • LogP   -0.5088
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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