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CS-W001157 4
Total: USD 88.00

Umbelliferone

  • CAS No. 93-35-6

  • Cat. No. CS-D1186
  • Molecule weight162.14
  • Purity≥98%
  • MDL No.MFCD00006878

*For research and further manufacturing use only, not for direct human use.

Umbelliferone|CS-D1186

Structure of 93-35-6

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General Information

  • CAS No. 93-35-6
  • Cat. No. CS-D1186
  • Purity ≥98%
  • MDL No. MFCD00006878
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₆O₃
  • Molecular Weight 162.14
  • Synonym(s) 7-Hydroxycoumarin; Hydrangin; NSC 19790
  • SMILES O=C1C=CC2=CC=C(O)C=C2O1

Description

.

Application

Umbelliferone serves as a versatile scaffold in synthetic organic chemistry, enabling efficient construction of coumarin-based frameworks through established lactonization and electrophilic substitution protocols. Its phenolic hydroxyl and carbonyl functionalities provide orthogonal handles for selective derivatization, while its inherent bench stability facilitates purification and handling in multi-step syntheses. Widely employed in medicinal chemistry and materials science, it functions as a key building block for bioactive heterocycles and fluorescent probes.

Synthesis

  • Route1
    • null|null
      617-48-1
    • null|null
      108-46-3
    • ~91%
    • In-stock
      Umbelliferone|CS-D1186
      93-35-6

    References

    • Symeonidis, Theodoros; Chamilos, Michael; Hadjipavlou-Litina, Dimitra J.; Kallitsakis, Michael; Litinas, Konstantinos E. Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 4 p. 1139 - 1142
  • Route2
    • 7-(Allyloxy)-2H-chromen-2-one|CS-0361066
      31005-03-5
    • ~97%
    • In-stock
      Umbelliferone|CS-D1186
      93-35-6

    References

    • Ganguly, Nemai C.; Dutta, Sanjoy; Datta, Mrityunjoy Tetrahedron Letters, 2006 , vol. 47, # 32 p. 5807 - 5810
  • Route3
    • null|null
      623-47-2
    • null|null
      108-46-3
    • ~82%
    • In-stock
      Umbelliferone|CS-D1186
      93-35-6

    References

    • Leao, Raquel A. C.; Def.demoraes, Paula; Pedro, Marcella C. B. C.; Costa, Paulo R. R. Synthesis, 2011 , # 22 art. no. M70011SS, p. 3692 - 3696

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   50.44
  • LogP   1.4986
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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