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Structure of 93117-07-8
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Inhibiting PARP-1 activity through covalent adduct formation, 5-AIQ hydrochloride (CAS 93117-07-8) suppresses excessive DNA repair consumption and reduces oxidative stress-induced hepatocyte necrosis in ischemia-reperfusion models.
5-AIQ hydrochloride (CAS 93117-07-8) inhibits poly (ADP-ribose) polymerase-1 (PARP-1) with high specificity, disrupting DNA damage response pathways in cancer cells. This inhibition triggers antiangiogenic effects. Researchers leverage this property to explore novel therapeutic strategies for solid tumors and retinal vascular disorders.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: