2-Chloro-N-methylaniline

Name: 2-Chloro-N-methylaniline
Brand: ChemScene
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CAS No. 932-32-1
Cat. No. CS-0095956
Purity≥95%
MDL No.MFCD00045170

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 932-32-1

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Description

2-Chloro-N-methylaniline features a chlorinated aromatic ring paired with a methylaniline functionality, delivering enhanced reactivity in electrophilic substitution and improved solubility over unsubstituted aniline analogs. This bench-stable compound integrates readily into pharmaceutical intermediates and specialty dye synthesis.

Application

2-Chloro-N-methylaniline serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling direct functionalization at the aromatic ring due to its activated chlorine substituent. The N-methyl group enhances solubility and modulates electronic properties, while the compound exhibits excellent bench stability and compatibility with standard coupling reactions. It functions as a key intermediate in constructing heterocyclic scaffolds and bioactive molecules via palladium-catalyzed cross-coupling or nucleophilic substitution.

General Information

CAS No. 932-32-1
Cat. No. CS-0095956
Purity ≥95%
MDL No. MFCD00045170
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₈ClN
Molecular Weight 141.60
Synonym(s) 1-(2-chlorophenyl)-N-methylmethanamine
SMILES CNC1=CC=CC=C1Cl

Computational Chemistry Data

TPSA 12.03
LogP 2.3817
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P305+P351+P338

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Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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2-Chloro-N-methylaniline

CAS No. 932-32-1

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