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CS-W001157 4
Total: USD 88.00

(Dichloroiodo)benzene

  • CAS No. 932-72-9

  • Cat. No. CS-0179660
  • Purity≥95%
  • MDL No.MFCD00009608

*For research and further manufacturing use only, not for direct human use.

(Dichloroiodo)benzene|CS-0179660

Structure of 932-72-9

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General Information

  • CAS No. 932-72-9
  • Cat. No. CS-0179660
  • Purity ≥95%
  • MDL No. MFCD00009608
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅Cl₂I
  • Molecular Weight None
  • Synonym(s) (Dichloroiodo)-benzene
  • SMILES ClI(C1=CC=CC=C1)Cl

Description

Dichloroiodo benzene serves as a direct source of the iodo group in transition metal-catalyzed cross-coupling reactions. This electrophilic iodide delivers high reactivity under mild conditions, enabling efficient C–C and C–heteroatom bond formation. The molecule features two chlorine atoms flanking the iodine center, enhancing its stability while maintaining compatibility with palladium and nickel catalysis.

Application

(Dichloroiodo)benzene serves as a reliable source of electrophilic iodine in transition-metal-catalyzed arylation reactions, enabling efficient C–H functionalization and direct arylation of heterocycles. Its bench-stable nature and compatibility with palladium and copper catalysis facilitate robust cross-coupling protocols, particularly in the synthesis of biaryl scaffolds and complex pharmaceutical intermediates.

Synthesis

  • Route1

    References

    • Gallos, John; Varvoglis, Anastasios Journal of Chemical Research, Miniprint, 1982 , # 6 p. 1649 - 1660
  • Route2
    • null|null
      106266-43-7
    • ~93%
    • In-stock
      (Dichloroiodo)benzene|CS-0179660
      932-72-9
    • In-stock
      2-Phenylacetamide|CS-W018983
      103-81-1

    References

    • Journal of Organic Chemistry, , vol. 52, # 3 p. 476 - 477
  • Route3

    References

    • Gallos, John; Varvoglis, Anastasios Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , p. 1999 - 2002

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P260-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   3.6702
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   1

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