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Structure of 932705-78-7
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5-Fluoro-6-methylnicotinic acid is a fluorinated nicotinic acid derivative featuring a methoxy group at the 6-position and a fluorine atom at the 5-position. This electron-deficient aromatic scaffold integrates readily into bioactive molecules, offering enhanced metabolic stability and improved membrane permeability in medicinal chemistry applications.
5-Fluoro-6-methylnicotinic acid serves as a valuable building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-fluoro and methyl substituents confer enhanced metabolic stability and modulate electronic properties, facilitating downstream functionalization via coupling reactions, amidation, or cyclization. The compound exhibits good bench stability and is readily purified by recrystallization, supporting scalable synthesis and integration into standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: