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Structure of 933716-45-1
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5-Bromo-1,3,4-thiadiazole-2-carboxylic acid features a brominated thiadiazole core paired with a carboxylic acid group, enabling direct conjugation in synthetic routes. The electron-deficient heterocycle facilitates nucleophilic substitution, while the carboxylic acid serves as a handle for amide coupling or esterification under standard conditions. This compound offers enhanced stability and solubility in polar solvents, supporting efficient integration into bioactive molecule scaffolds.
5-Bromo-1,3,4-thiadiazole-2-carboxylic acid serves as a versatile building block in medicinal chemistry and heterocyclic synthesis. Its bromine substituent enables palladium-catalyzed cross-coupling reactions, while the carboxylic acid group facilitates amide formation, esterification, and direct derivatization. The molecule exhibits bench stability, good functional group tolerance, and compatibility with standard purification methods, making it ideal for iterative synthesis of bioactive thiadiazole scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: