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Structure of 934-59-8
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5-Nitropyridin-3-amine features a pyridine core bearing both an electron-deficient nitro group and a nucleophilic amine at adjacent positions, enabling strategic functionalization in heterocyclic synthesis. This dual-functional scaffold facilitates coupling reactions and serves as a key intermediate in medicinal chemistry and materials science applications.
5-Nitropyridin-3-amine serves as a versatile building block in medicinal chemistry, enabling direct incorporation into heterocyclic scaffolds via nucleophilic substitution or metal-catalyzed coupling reactions. The ortho-nitro and amino groups provide complementary reactivity for sequential functionalization, while the molecule exhibits sufficient bench stability for routine handling and purification. Its dual functionality facilitates access to diverse pyridine-based pharmacophores.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: