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Structure of 935685-88-4
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3-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile features a boronate ester group flanked by electron-withdrawing fluorine and nitrile functionalities, enabling robust coupling in Suzuki-Miyaura reactions. This bench-stable reagent integrates seamlessly into complex molecular architectures under mild conditions.
3-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile serves as a versatile boronate building block in Suzuki-Miyaura cross-coupling reactions. The tetramethylboronate group enables efficient coupling with aryl and heteroaryl halides under mild conditions, while the fluorinated benzene core provides metabolic stability and favorable electronic properties. The nitrile functionality offers additional handle for downstream transformations. Bench-stable and readily purified by flash chromatography, it facilitates rapid assembly of complex biaryl scaffolds common in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
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Lot numbers can be found on the outside label of a product: