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Structure of 936-02-7
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2-Hydroxybenzohydrazide features a phenolic hydroxyl and hydrazide functional group in close proximity, enabling chelation with metal ions and participation in condensation reactions. This structural motif supports its use in coordination chemistry and as a building block for bioactive heterocycles.
2-Hydroxybenzohydrazide serves as a versatile building block in the synthesis of heterocyclic scaffolds, particularly oxadiazoles and triazoles, via cyclization reactions. Its ortho-hydroxyl and hydrazide functionalities enable efficient, one-step condensation with carboxylic acid derivatives or carbonyl compounds under mild conditions. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative medicinal chemistry campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: