Lot numbers can be found on the outside label of a product:
6-Chloro-2-cyano-3-nitropyridine
-
CAS No. 93683-65-9
- Cat. No. CS-0022422
- Purity≥97%
- MDL No.MFCD06657641
*For research and further manufacturing use only, not for direct human use.
Structure of 93683-65-9
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 93683-65-9
- Cat. No. CS-0022422
- Purity ≥97%
- MDL No. MFCD06657641
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₆H₂ClN₃O₂
- Molecular Weight 183.55
- Synonym(s) 6-chloro-3-nitropyridine-2-carbonitrile
- SMILES N#CC1=NC(Cl)=CC=C1[N+]([O-])=O
Description
6-Chloro-2-cyano-3-nitropyridine is a versatile heterocyclic building block featuring a chloro group at the 6-position, a cyano moiety at C2, and a nitro substituent at C3. This electronic profile enables efficient coupling reactions and facilitates downstream functionalization in medicinal chemistry and agrochemical synthesis. The molecule exhibits stability under standard bench conditions and compatibility with diverse reaction environments.
Application
6-Chloro-2-cyano-3-nitropyridine serves as a versatile building block in heterocyclic synthesis, enabling efficient access to substituted pyridine scaffolds via palladium-catalyzed cross-coupling and nucleophilic substitution reactions. The chloro group facilitates direct functionalization, while the cyano and nitro groups provide orthogonal reactivity for further derivatization. Its bench-stable nature and compatibility with standard synthetic protocols make it well-suited for medicinal chemistry and process development workflows.
Synthesis
-
Route1
-
In-stock
16013-85-7 - ~64%
-
In-stock
93683-65-9
References
-
PIERRE FABRE MEDICAMENT; KRUCZYNSKI, Anna; CREANCIER, Laurent; KALOUN, El Bachir; BEDJEGUELAL, Karim; RABOT, Rémi Patent: WO2014/16434 A1, 2014 ; Location in patent: Page/Page column 61-62 ;
-
-
Route2
-
In-stock
16013-85-7
-
544-92-3 - ~57%
-
In-stock
93683-65-9
References
-
Colbry; Elslager; Werbel Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 5 p. 1521 - 1525
-
-
References
-
PIERRE FABRE MEDICAMENT; KALOUN, El Bachir; BEDJEGUELAL, Karim; RABOT, Rémi; KRUCZYNSKI, Anna; SCHMITT, Philippe; PEREZ, Michel; RAHIER, Nicolas Patent: US2013/85144 A1, 2013 ; Location in patent: Paragraph 0350; 0351 ;
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 79.82
- LogP 1.51488
- H_Acceptors 4
- H_Donors 0
- Rotatable_Bonds 1
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 6-Chloro-2-cyano-3-nitropyridine sigma6-Chloro-2-cyano-3-nitropyridine manufacturer6-Chloro-2-cyano-3-nitropyridine price6-Chloro-2-cyano-3-nitropyridine structure6-Chloro-2-cyano-3-nitropyridine SDSbuy 6-Chloro-2-cyano-3-nitropyridine6-Chloro-2-cyano-3-nitropyridine supplier6-Chloro-2-cyano-3-nitropyridine uses6-Chloro-2-cyano-3-nitropyridine molecular weightprice of 6-Chloro-2-cyano-3-nitropyridine6-Chloro-2-cyano-3-nitropyridine chemical name formula of 6-Chloro-2-cyano-3-nitropyridine