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Structure of 369-36-8
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2-Fluoro-5-nitroaniline features a fluorine atom at the ortho position relative to the amino group and a nitro group at the meta position, creating a strongly electron-deficient aromatic system. This combination enhances reactivity in electrophilic substitution and facilitates coupling reactions under mild conditions. The molecule exhibits bench-stable handling characteristics and integrates readily into advanced synthetic sequences for pharmaceutical intermediates and functional materials.
2-Fluoro-5-nitroaniline serves as a key building block for fluorinated heterocycles and pharmaceutical intermediates, enabling direct coupling reactions via its amino and nitro functionalities. Its bench-stable nature and compatibility with Pd-catalyzed cross-coupling protocols facilitate efficient synthesis of complex arylated scaffolds. Functional group tolerance supports sequential transformations in multi-step sequences.
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GHS Pictogram :
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GHS No : GHS02,GHS07
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Signal Word : Danger
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UN#: 1325
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Class : 4.1
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Packing Group : Ⅱ
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Hazard Statements : H228-H315-H319-H335
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Precautionary Statements : P210-P240-P241-P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: