DMT-dI

Name: DMT-dI
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 93778-57-5
Cat. No. CS-W011460
Purity≥98%
MDL No.MFCD00057879

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HazMat Fee

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Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

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Description

DMT-dI delivers a robust, bench-stable phosphoramidite for rapid oligonucleotide synthesis. This derivative features a protected 5′-hydroxyl group and a dimethoxytrityl (DMT) chromophore, enabling efficient coupling and real-time monitoring during solid-phase assembly. The dI moiety ensures high incorporation fidelity and compatibility with standard deprotection protocols.

Application

DMT-dI serves as a reliable building block for the synthesis of nucleoside analogs, enabling efficient coupling reactions under standard phosphoramidite conditions. Its dimethoxytrityl (DMT) group provides excellent protection and facilitates purification via chromatography, while the deoxyinosine (dI) moiety offers a stable, functionally versatile scaffold for oligonucleotide assembly and medicinal chemistry applications.

General Information

CAS No. 93778-57-5
Cat. No. CS-W011460
Purity ≥98%
MDL No. MFCD00057879
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₃₁H₃₀N₄O₆
Molecular Weight 554.59
Synonym(s) 5'-O-DMT-dI; 2'-Deoxy-5'-O-DMT-inosine
SMILES O[C@H]1C[C@H](N2C(N=CNC3=O)=C3N=C2)O[C@@H]1COC(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6

Computational Chemistry Data

TPSA 120.72
LogP 3.7939
H_Acceptors 9
H_Donors 2
Rotatable_Bonds 9

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Other Classifications

Life Science Nucleosides & Nucleotides 5'-Protected Nucleosides

Chemical Biology Nucleic Acid Chemistry Protected Nucleosides

Biochemistry Biochemicals and Reagents Nucleosides, Nucleotides, Oligonucleotides Nucleobases and their Analogs

Biochemistry Biochemicals and Reagents Nucleosides, Nucleotides, Oligonucleotides Nucleoside Analogs

Biochemistry Biochemicals and Reagents Nucleosides, Nucleotides, Oligonucleotides Nucleosides

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DMT-dI

CAS No. 93778-57-5

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