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Structure of 942077-16-9
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3-Cyano-5-(trifluoromethyl)benzoic acid features a trifluoromethyl group and a nitrile moiety positioned ortho to the carboxylic acid, creating a strongly electron-deficient aromatic core. This combination enhances its utility in coupling reactions and as a building block for bioactive molecules requiring high metabolic stability and precise electronic tuning.
3-Cyano-5-(trifluoromethyl)benzoic acid serves as a versatile building block in medicinal chemistry and materials science, offering a robust combination of electron-withdrawing groups that enhance both metabolic stability and binding affinity. Its carboxylic acid functionality enables straightforward derivatization via esterification, amide coupling, or direct salt formation, while the cyano and trifluoromethyl groups provide excellent functional group tolerance and synthetic handle diversity. The molecule exhibits good bench stability and ease of purification, making it well-suited for scale-up and integration into complex synthetic sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: