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CS-W001157 4
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tert-Butyl (S)-1-azido-3-((R)-tetrahydro-2H-pyran-3-yl)propan-2-ylcarbamate

  • CAS No. 942145-24-6

  • Cat. No. CS-M0729
  • Molecule weight284.35
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (S)-1-azido-3-((R)-tetrahydro-2H-pyran-3-yl)propan-2-ylcarbamate|CS-M0729

Structure of 942145-24-6

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General Information

  • CAS No. 942145-24-6
  • Cat. No. CS-M0729
  • Purity ≥98%
  • MDL No. None
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₄N₄O₃
  • Molecular Weight 284.35
  • Synonym(s) CarbaMic acid, N-[(1S)-1-(azidoMethyl)-2-[(3R)-tetrahydro-2H-pyran-3-yl]ethyl]-, 1,1-diMethylethyl ester
  • SMILES CC(C)(C)OC(N[C@@H](C[C@@H]1COCCC1)CN=[N+]=[N-])=O

Synthesis

  • Route1

    References

    • Jia, Lanqi; Simpson, Robert D.; Yuan, Jing; Xu, Zhenrong; Zhao, Wei; Cacatian, Salvacion; Tice, Colin M.; Guo, Joan; Ishchenko, Alexey; Singh, Suresh B.; Wu, Zhongren; McKeever, Brian M.; Bukhtiyarov, Yuri; Johnson, Judith A.; Doe, Christopher P.; Harrison, Richard K.; McGeehan, Gerard M.; Dillard, Lawrence W.; Baldwin, John J.; Claremon, David A. ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 10 p. 747 - 751
  • Route2
    • 1-(tert-Butyl) 2-ethyl (2S,4R)-4-allyl-5-oxopyrrolidine-1,2-dicarboxylate|CS-0778920
      153080-81-0
    • ~%
    • tert-Butyl (S)-1-azido-3-((R)-tetrahydro-2H-pyran-3-yl)propan-2-ylcarbamate|CS-M0729
      942145-24-6

    References

    • Jia, Lanqi; Simpson, Robert D.; Yuan, Jing; Xu, Zhenrong; Zhao, Wei; Cacatian, Salvacion; Tice, Colin M.; Guo, Joan; Ishchenko, Alexey; Singh, Suresh B.; Wu, Zhongren; McKeever, Brian M.; Bukhtiyarov, Yuri; Johnson, Judith A.; Doe, Christopher P.; Harrison, Richard K.; McGeehan, Gerard M.; Dillard, Lawrence W.; Baldwin, John J.; Claremon, David A. ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 10 p. 747 - 751

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   96.32
  • LogP   3.0067
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   5

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