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Structure of 944317-53-7
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4-Methyl-5-nitro-2-(trifluoromethyl)pyridine features a trifluoromethyl group at the 2-position and a nitro substituent at the 5-position, creating a highly electron-deficient pyridine core. This combination enhances its utility in cross-coupling reactions and as a building block for functionalized heterocycles in medicinal chemistry. The methyl group at the 4-position provides steric control and modulates reactivity. The molecule exhibits bench-stable handling under standard conditions.
4-Methyl-5-nitro-2-(trifluoromethyl)pyridine serves as a versatile building block in medicinal chemistry, enabling efficient construction of functionalized heterocycles via cross-coupling and nucleophilic substitution. Its trifluoromethyl and nitro groups provide strong electron-withdrawing character, enhancing reactivity in palladium-catalyzed transformations. Bench-stable and readily purified by column chromatography, it facilitates scalable synthesis of advanced API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H320-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: