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Structure of 944347-13-1
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2-Fluoro-1H-indole features a fluorine atom at the 2-position of the indole scaffold, imparting enhanced electron-withdrawing character and metabolic stability. This substitution pattern enables direct incorporation into bioactive molecules, particularly in pharmaceuticals and agrochemicals where modulated lipophilicity and electronic properties are critical. The compound exhibits robust bench stability and compatibility with standard synthetic transformations.
2-Fluoro-1H-indole serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C2 position via electrophilic substitution or transition-metal-catalyzed coupling. Its fluorinated indole core imparts enhanced metabolic stability and modulated electronic properties, making it valuable for constructing bioactive heterocycles. The compound exhibits good bench stability and compatibility with common reaction conditions, facilitating efficient incorporation into diverse scaffolds through standard synthetic protocols.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H302-H315-H318-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: