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Structure of 944898-49-1
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5-Fluoro-benzooxazole-2-carboxylic acid features a fluorinated benzooxazole core with a carboxylic acid at the 2-position, offering enhanced electron-withdrawing character and improved solubility in polar solvents. This structural motif enables efficient coupling reactions in pharmaceutical synthesis, particularly in constructing bioactive heterocycles under mild conditions.
5-Fluoro-benzooxazole-2-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles through standard amide coupling and electrophilic substitution reactions. Its fluorinated aromatic core enhances metabolic stability and modulates electronic properties, while the carboxylic acid functionality facilitates direct conjugation or derivatization. The compound exhibits excellent bench stability and compatibility with common purification protocols, making it well-suited for high-throughput screening and lead optimization workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: