nNOS-IN-1

Name: nNOS-IN-1
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 945762-00-5
Cat. No. CS-0040362
Purity≥98%
MDL No.MFCD11848409

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Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 945762-00-5

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Description

nNOS-IN-1 is a potent, selective inhibitor of neuronal nitric oxide synthase, designed for precise modulation of NO signaling pathways. This compound exhibits high affinity for nNOS over other NOS isoforms, enabling targeted investigation of neuroinflammatory and neurodegenerative processes in preclinical models.

Application

nNOS-IN-1 serves as a well-characterized, selective inhibitor of neuronal nitric oxide synthase (nNOS), enabling targeted investigation of nitric oxide-mediated signaling pathways in neurological and inflammatory contexts. Its stability and cell-permeable properties facilitate consistent performance in cellular assays and in vivo models, supporting mechanistic studies in neurodegenerative disease research and vascular physiology.

General Information

CAS No. 945762-00-5
Cat. No. CS-0040362
Purity ≥98%
MDL No. MFCD11848409
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₄BrN₃
Molecular Weight 222.04
Synonym(s) None
SMILES N#CC1=CC=CC2=C1NN=C2Br

Computational Chemistry Data

TPSA 52.47
LogP 2.19708
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Cyanide/Nitrile

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Indazole compounds

Key Words

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nNOS-IN-1

CAS No. 945762-00-5

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