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4-(3-(Methylamino)-1-(thiophen-2-yl)propyl)naphthalen-1-ol Duloxetine Impurity

  • CAS No. 949095-98-1

  • Cat. No. CS-0379889
  • Molecule weight297.41
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-(3-(Methylamino)-1-(thiophen-2-yl)propyl)naphthalen-1-ol Duloxetine Impurity|CS-0379889

Structure of 949095-98-1

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General Information

  • CAS No. 949095-98-1
  • Cat. No. CS-0379889
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₈H₁₉NOS
  • Molecular Weight 297.41
  • Synonym(s) None
  • SMILES OC1=C2C=CC=CC2=C(C(C3=CC=CS3)CCNC)C=C1

Synthesis

  • Route1
    • Duloxetine impurity 3 hydrobromide|CS-0531682
      949096-01-9
    • ~96%
    • 4-(3-(Methylamino)-1-(thiophen-2-yl)propyl)naphthalen-1-ol Duloxetine Impurity|CS-0379889
      949095-98-1

    References

    • EGIS GYOGYSZERGYAR NYRT Patent: WO2007/105021 A2, 2007 ; Location in patent: Page/Page column 31 ;
  • Route2

    References

    • Biswas, Sujoy; Karanjai, Keya Patent: US2009/275760 A1, 2009 ; Location in patent: Page/Page column 4 ;
  • Route3

    References

    • Ranbaxy Laboratories Limited Patent: EP2107057 A1, 2009 ; Location in patent: Page/Page column 5 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS06,GHS09
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H302-H311-H315-H318-H335-H411
Precautionary Statements : P273-P280-P302+P352-P391

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Computational Chemistry Data

  • TPSA   32.26
  • LogP   4.3483
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   5

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