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Structure of 94977-52-3
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(E)-3-(2,4-Difluorophenyl)acrylic acid features a conjugated olefinic linkage flanked by an electron-deficient aryl group and a carboxylic acid terminus. This structural motif enables direct participation in cross-coupling reactions and serves as a key scaffold for bioactive molecule synthesis under standard conditions.
(E)-3-(2,4-Difluorophenyl)acrylic acid serves as a versatile building block for conjugated systems and heterocyclic scaffolds. Its stabilized enoate geometry enables reliable Michael additions and Diels–Alder reactions. The ortho-difluoro substitution enhances metabolic stability and modulates electronic properties, making it valuable in medicinal chemistry synthesis. Bench-stable and readily purified by recrystallization, it functions effectively in standard coupling and functionalization workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: