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Structure of 950514-14-4
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Methyl 2-oxo-1,2-dihydropyrimidine-4-carboxylate serves as a key scaffold in heterocyclic synthesis, featuring a conjugated enone system and a readily functionalizable ester group. This bench-stable, moisture-tolerant building block integrates efficiently into multistep transformations, enabling access to pyrimidine derivatives with defined substitution patterns.
Methyl 2-oxo-1,2-dihydropyrimidine-4-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling efficient access to pyrimidine scaffolds prevalent in medicinal chemistry. Its reactive enolizable carbonyl and electron-deficient C4 position facilitate nucleophilic addition, cycloadditions, and transition-metal-catalyzed couplings. The methyl ester group offers synthetic flexibility for further derivatization, while the compound exhibits good bench stability and ease of purification—ideal for iterative synthesis campaigns.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: