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CS-W001157 4
Total: USD 88.00

2,3-Dichloropyridine-4-boronic acid

  • CAS No. 951677-39-7

  • Cat. No. CS-W010716
  • Purity≥97%
  • MDL No.MFCD04038756
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2,3-Dichloropyridine-4-boronic acid|CS-W010716

Structure of 951677-39-7

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Description

2,3-Dichloropyridine-4-boronic acid features a boronate group flanked by two chlorine substituents on the pyridine ring, enabling direct coupling in Suzuki-Miyaura reactions. The electron-deficient heterocycle enhances reactivity while maintaining bench-stability under standard conditions. This configuration facilitates efficient incorporation into complex molecular architectures.

Application

2,3-Dichloropyridine-4-boronic acid serves as a versatile building block in cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl scaffolds. The boronic acid group facilitates Suzuki-Miyaura coupling under mild conditions, while the dichloropyridine motif provides orthogonal reactivity for downstream functionalization. Bench-stable and readily purified, it is well-suited for medicinal chemistry and process development workflows requiring precise control over substitution patterns.

General Information

  • CAS No. 951677-39-7
  • Cat. No. CS-W010716
  • Purity ≥97%
  • MDL No. MFCD04038756
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₄BCl₂NO₂
  • Molecular Weight 191.80
  • Synonym(s) boronic acid, B-(2,3-dichloro-4-pyridinyl)-
  • SMILES OB(O)C1=C(Cl)C(Cl)=NC=C1

Computational Chemistry Data

  • TPSA   53.35
  • LogP   0.0682
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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