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Structure of 952182-51-3
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This trifluoromethyl-substituted quinoline carboxylic acid features a strongly electron-deficient heterocyclic core paired with a reactive carboxyl group, enabling direct coupling in late-stage functionalization. The para-trifluoromethyl motif enhances metabolic stability and modulates lipophilicity, making it valuable for medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds.
2-(Trifluoromethyl)quinoline-6-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and functionalization reactions. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the carboxylic acid facilitates direct derivatization or amide formation. The molecule exhibits good bench stability and compatibility with common reaction conditions, supporting efficient synthesis of potential pharmaceutical candidates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: