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CS-W001157 4
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tert-Butyl 2,8-diazaspiro[5.5]undecane-2-carboxylate

  • CAS No. 954240-14-3

  • Cat. No. CS-D0623
  • Purity≥98%
  • MDL No.MFCD09701315
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 2,8-diazaspiro[5.5]undecane-2-carboxylate|CS-D0623

Structure of 954240-14-3

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Description

tert-Butyl 2,8-diazaspiro[5.5]undecane-2-carboxylate features a rigid spirocyclic scaffold with two nitrogen atoms positioned at key junctions, enabling precise stereocontrol in asymmetric synthesis. The tert-butyl ester group offers excellent stability and ease of deprotection under mild acidic conditions. This compound serves as a versatile chiral building block for medicinal chemistry applications, particularly in the development of macrocyclic inhibitors and bioactive small molecules.

Application

tert-Butyl 2,8-diazaspiro[5.5]undecane-2-carboxylate serves as a versatile spirocyclic scaffold for medicinal chemistry, enabling the construction of constrained bicyclic systems with defined stereochemistry. The protected diamine functionality offers orthogonal reactivity, facilitating selective derivatization and incorporation into bioactive molecules. Its bench-stable nature and compatibility with standard coupling protocols make it well-suited for modular synthesis workflows.

General Information

  • CAS No. 954240-14-3
  • Cat. No. CS-D0623
  • Purity ≥98%
  • MDL No. MFCD09701315
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₆N₂O₂
  • Molecular Weight 254.37
  • Synonym(s) tert-Butyl-2,8-diazaspiro[5.5]undecan-2-carboxylat
  • SMILES O=C(OC(C)(C)C)N(CCC1)CC21CNCCC2

Computational Chemistry Data

  • TPSA   41.57
  • LogP   2.3871
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302+H312+H332-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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