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Structure of 957034-38-7
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This boronate moiety features a trifluoromethyl group at the para position, enhancing electron deficiency and metabolic stability. The bromine substituent enables efficient palladium-catalyzed cross-coupling reactions under standard conditions. This bench-stable reagent integrates seamlessly into Suzuki-Miyaura coupling workflows for constructing complex aryl scaffolds in medicinal chemistry and materials science.
(2-Bromo-5-(trifluoromethyl)phenyl)boronic acid serves as a versatile building block in palladium-catalyzed cross-coupling reactions, enabling efficient construction of biaryl architectures. Its compatibility with Suzuki-Miyaura coupling conditions facilitates the synthesis of substituted aromatic scaffolds with enhanced metabolic stability. The bromo and trifluoromethyl groups provide orthogonal reactivity for sequential functionalization, while the boronic acid moiety offers excellent bench stability and ease of purification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: