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Structure of 957065-87-1
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This boronic acid features a difluorinated aromatic ring paired with a hydroxyl group, enabling enhanced solubility and stability in aqueous environments. The para-hydroxy functionality facilitates direct coupling in Suzuki-Miyaura reactions, while the ortho-fluorine substituents improve reactivity through electronic activation. Designed for bench-stable handling, it integrates efficiently into complex synthesis workflows requiring precise functional group compatibility.
(2,6-Difluoro-4-hydroxyphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of substituted biaryls and heteroaryl architectures. The ortho-difluoro substitution enhances electrophilic reactivity and improves metabolic stability in downstream pharmaceutical candidates. Its boronic acid functionality offers excellent bench stability, compatibility with diverse reaction conditions, and straightforward purification via standard aqueous workup.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: