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Structure of 957120-32-0
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This boronate moiety features a 5-fluoro-2-methoxypyridin-3-yl scaffold, delivering enhanced stability and compatibility in cross-coupling reactions. The electron-deficient pyridine ring facilitates efficient palladium-catalyzed transformations, while the methoxy group improves solubility and modulates reactivity. A bench-stable reagent ideal for constructing complex heterocyclic architectures in medicinal chemistry and materials science.
(5-Fluoro-2-methoxypyridin-3-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient C–C bond formation with aryl and vinyl halides. The fluorinated pyridine core provides enhanced metabolic stability and modulates electronic properties, while the methoxy group offers orthogonal reactivity and improved solubility. Bench-stable and readily purified by flash chromatography or recrystallization, it functions reliably in late-stage functionalization and heterocyclic scaffold elaboration for medicinal chemistry applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: