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(2R,3R)-3-Aminobutan-2-ol hydrochloride

  • CAS No. 960008-54-2

  • Cat. No. CS-0133760
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(2R,3R)-3-Aminobutan-2-ol hydrochloride|CS-0133760

Structure of 960008-54-2

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General Information

  • CAS No. 960008-54-2
  • Cat. No. CS-0133760
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₁₂ClNO
  • Molecular Weight 125.60
  • Synonym(s) (2R,3R)-3-AMINO-2-BUTANOL HYDROCHLORIDE
  • SMILES C[C@@H](O)[C@H](N)C.[H]Cl

Description

(2R,3R)-3-Aminobutan-2-ol hydrochloride is a chiral amino alcohol featuring a stereodefined secondary amine and hydroxyl group in a 1,2-diols arrangement. This bench-stable salt delivers a rigid, enantioselective scaffold for asymmetric synthesis, integrating seamlessly into catalytic systems and peptide-like architectures.

Application

(2R,3R)-3-Aminobutan-2-ol hydrochloride serves as a stereochemically defined chiral building block for the synthesis of bioactive molecules, enabling efficient access to β-amino alcohol motifs prevalent in medicinal chemistry. The hydrochloride salt enhances bench stability and simplifies purification, while the protected amine and vicinal hydroxyl group offer orthogonal reactivity for downstream functionalization. Its well-established synthetic utility supports applications in peptide analogs, kinase inhibitors, and heterocyclic scaffold construction.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

  • TPSA   46.25
  • LogP   0.1362
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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