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CS-W001157 4
Total: USD 88.00

2,4,6-Tri-tert-butylaniline

  • CAS No. 961-38-6

  • Cat. No. CS-W021499
  • Purity≥97%
  • MDL No.MFCD00011645

*For research and further manufacturing use only, not for direct human use.

2,4,6-Tri-tert-butylaniline|CS-W021499

Structure of 961-38-6

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General Information

  • CAS No. 961-38-6
  • Cat. No. CS-W021499
  • Purity ≥97%
  • MDL No. MFCD00011645
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₈H₃₁N
  • Molecular Weight 261.45
  • Synonym(s) None
  • SMILES C1=C(C(C)(C)C)C=C(C(=C1C(C)(C)C)N)C(C)(C)C

Description

2,4,6-Tri-tert-butylnitrobenzene (bulky amine) was used in the synthesis of monomeric iminophosphorane.

Application

2,4,6-Tri-tert-butylaniline serves as a sterically hindered aromatic amine enabling controlled functionalization in demanding synthetic contexts. Its three bulky tert-butyl groups provide exceptional steric shielding, enhancing stability and minimizing undesired side reactions. This compound functions effectively in electrophilic substitution studies and acts as a valuable building block for high-throughput screening libraries and specialized catalysts requiring extreme steric protection.

Synthesis

  • Route1

    References

    • Underiner, Gail E.; Tan, Robin P.; Powell, Douglas R.; West, Robert Journal of the American Chemical Society, 1991 , vol. 113, # 22 p. 8437 - 8443
  • Route2

    References

    • Journal of the American Chemical Society, , vol. 104, # 25 p. 7191 - 7195
  • Route3
    • null|null
      24973-59-9
    • ~27%
    • In-stock
      2,4,6-Tri-tert-butylaniline|CS-W021499
      961-38-6

    References

    • Ferreira, Luisa M.; Marques, M. Manuel B.; Gloria, Paulo M.C.; Chaves, Humberto T.; Franco, Joao-Pedro P.; Mourato, Isabel; Antunes, Jose-Rafael T.; Rzepa, Henry S.; Lobo, Ana M.; Prabhakar, Sundaresan Tetrahedron, 2008 , vol. 64, # 33 p. 7759 - 7770

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   5.1613
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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