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Structure of 98102-32-0
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H-Glu(OtBu)-OBzl.HCl is a protected glutamic acid derivative featuring a tert-butyl ester and benzyl ether group, offering enhanced stability and solubility in organic solvents. This orthogonal protection scheme facilitates selective deprotection during peptide synthesis, enabling efficient access to functionalized glutamate residues under standard conditions.
H-Glu(OtBu)-OBzl.HCl serves as a versatile, bench-stable building block for the synthesis of peptide-based pharmaceutical intermediates and complex heterocyclic scaffolds. The side-chain γ-carboxyl group is protected as a tert-butyl ester, while the α-amino group is protonated as a hydrochloride salt, enabling straightforward coupling reactions and orthogonal deprotection sequences. Its compatibility with standard Fmoc and Boc solid-phase peptide synthesis protocols facilitates efficient incorporation into target molecules.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: