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Structure of 98475-10-6
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1,3-Dihydro-2-benzofuran-4-amine features a fused bicyclic scaffold with a primary amine at the 4-position, enabling direct functionalization in medicinal chemistry. The electron-rich aromatic system enhances reactivity in coupling reactions, while the saturated dihydrofuran ring provides conformational rigidity and improved metabolic stability. This compound serves as a key building block for bioactive heterocycles, particularly in kinase inhibitor and CNS-targeted drug discovery.
1,3-Dihydro-2-benzofuran-4-amine serves as a versatile scaffold in medicinal chemistry, enabling efficient access to bioactive heterocycles. Its electron-rich aromatic system and amine functionality facilitate direct functionalization and coupling reactions, while its bench-stable nature supports reliable handling and purification. The compound functions as a key building block for synthesizing fused polycyclic systems and pharmacologically relevant frameworks through standard amidation, alkylation, and cross-coupling protocols.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501
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Lot numbers can be found on the outside label of a product: