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Structure of 98485-37-1
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3-Ethyloxetane-3-carbaldehyde is a bench-stable, moisture-tolerant heterocyclic aldehyde featuring a strained oxetane ring fused to an ethyl-substituted carbonyl group. This unique structural motif enables direct incorporation into complex molecular architectures via nucleophilic addition or cycloaddition reactions. The aldehyde functionality provides a reactive handle for conjugation with amines or hydrazides, facilitating the synthesis of bioconjugates and functionalized polymers under mild conditions.
3-Ethyloxetane-3-carbaldehyde serves as a versatile synthon in medicinal chemistry, enabling efficient access to oxetane-containing scaffolds via [3+2] cycloadditions and nucleophilic additions. Its aldehyde functionality facilitates direct functionalization or conversion to imines and hydrazones, while the strained oxetane ring enhances metabolic stability and solubility in drug candidates. The molecule exhibits good bench stability and compatibility with common protecting groups, supporting straightforward purification and integration into multi-step synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: