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CS-W001157 4
Total: USD 88.00

2-Methoxy-5-nitroaniline

  • CAS No. 99-59-2

  • Cat. No. CS-0015286
  • Purity≥97%
  • MDL No.MFCD00007261

*For research and further manufacturing use only, not for direct human use.

2-Methoxy-5-nitroaniline|CS-0015286

Structure of 99-59-2

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General Information

  • CAS No. 99-59-2
  • Cat. No. CS-0015286
  • Purity ≥97%
  • MDL No. MFCD00007261
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈N₂O₃
  • Molecular Weight 168.15
  • Synonym(s) Methoxynitroaniline
  • SMILES NC1=CC([N+]([O-])=O)=CC=C1OC

Description

2-Methoxy-5-nitroaniline features a para-substituted aromatic core with complementary electron-withdrawing nitro and electron-donating methoxy groups, enabling precise tuning of reactivity in cross-coupling and electrophilic substitution reactions. This bench-stable derivative integrates readily into complex molecular architectures under standard conditions.

Synthesis

  • Route1
    • null|null
      119-27-7
    • ~85%
    • In-stock
      2-Methoxy-5-nitroaniline|CS-0015286
      99-59-2

    References

    • Barrows, Susan E.; Cramer, Christopher J.; Truhlar, Donald G.; Elovitz, Michael S.; Weber, Eric J. Environmental Science and Technology, 1996 , vol. 30, # 10 p. 3028 - 3038
  • Route2
    • null|null
      90-04-0
    • ~77%
    • In-stock
      2-Methoxy-5-nitroaniline|CS-0015286
      99-59-2

    References

    • Gorelik; Shteiman; Shner; Romanskii; Kuznetsova Russian Journal of Organic Chemistry, 1997 , vol. 33, # 3 p. 348 - 352
  • Route3
    • null|null
      119-27-7
    • ~29%
    • In-stock
      4-Methoxy-3-nitroaniline|CS-W002411
      577-72-0
    • In-stock
      2-Methoxy-5-nitroaniline|CS-0015286
      99-59-2

    References

    • Tetrahedron Letters, , vol. 35, # 42 p. 7867 - 7870

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS08
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335-H351-H361
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   78.39
  • LogP   1.1856
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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