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5-(Methylthio)thiazol-2-amine

  • CAS No. 99171-11-6

  • Cat. No. CS-0150103
  • Molecule weight146.23
  • Purity≥95%
  • MDL No.MFCD09943153

*For research and further manufacturing use only, not for direct human use.

5-(Methylthio)thiazol-2-amine|CS-0150103

Structure of 99171-11-6

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General Information

  • CAS No. 99171-11-6
  • Cat. No. CS-0150103
  • Purity ≥95%
  • MDL No. MFCD09943153
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₆N₂S₂
  • Molecular Weight 146.23
  • Synonym(s) Thiazole, 2-amino-5-(methylthio)- (6CI)
  • SMILES CSC1=CNC(=N)S1

Synthesis

  • Route1

    References

    • Romark Laboratories, L.C. Patent: US2012/108591 A1, 2012 ; Location in patent: Page/Page column 32 ;
  • Route2
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    • 5-(Methylthio)thiazol-2-amine|CS-0150103
      99171-11-6

    References

    • Kitas, Eric; Mohr, Peter; Kuhn, Bernd; Hebeisen, Paul; Wessel, Hans Peter; Haap, Wolfgang; Ruf, Armin; Benz, Joerg; Joseph, Catherine; Huber, Walter; Sanchez, Ruben Alvarez; Paehler, Axel; Benardeau, Agnes; Gubler, Marcel; Schott, Brigitte; Tozzo, Effie Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 2 p. 594 - 599
  • Route3

    References

    • Stachulski, Andrew V.; Pidathala, Chandrakala; Row, Eleanor C.; Sharma, Raman; Berry, Neil G.; Iqbal, Mazhar; Bentley, Joanne; Allman, Sarah A.; Edwards, Geoffrey; Helm, Alison; Hellier, Jennifer; Korba, Brent E.; Semple, J. Edward; Rossignol, Jean-Francois Journal of Medicinal Chemistry, 2011 , vol. 54, # 12 p. 4119 - 4132

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

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Computational Chemistry Data

  • TPSA   39.64
  • LogP   1.27757
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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